992 The prevalence of human papillomavirus (HPV) DNA in male genital lichen sclerosus (MGLSc)

MGLSc is an acquired, chronic skin disease that can lead to sexual dysfunction and urological morbidity. Although both MGLSc and HPV are considered risk factors for penile cancer, no clear link has been found between the two. To further investigate the possibility of an association we correlated the presence of MGLSc and HPV across the prepuce. Preputial fresh frozen samples were collected from nine patients with clinically diagnosed MGLSc. The specimens were divided into a grid and biopsies were obtained to determine the spatial distribution of MGLSc and for HPV DNA sequencing.

Source: Journal of Investigative Dermatology - April 17, 2023 Category: Dermatology Authors: G. Kravvas, C. Ganier, H. van den Munckhof, M. de Koning, W. Quint, A. Freeman, A. Haider, H. Alnajjar, A. Muneer, M. Lynch, C. Bunker Source Type: research