1613 Detection of skin allergy biomarkers for point of care diagnosis of contact dermatitis

Contact Dermatitis (CD) is a one of the most common inflammatory skin diseases. Distinguishing the different types of CD, especially allergic CD (ACD) versus non-allergic forms, including irritant CD (ICD), is often challenging and requires additional investigations based on patch-testing. Early detection of relevant allergy biomarkers in active CD lesions could help to refine and simplify the management of CD patients. To characterize the molecular signatures of active CD lesions, we studied the expression of 12 allergy biomarkers (identified in a recent transcriptomic study) by qRT-PCR in eczema lesions of 25 CD patients.
Source: Journal of Investigative Dermatology - Category: Dermatology Authors: Source Type: research