Topic of concern in TMS research: Cases of mismatch between indicated and actual current direction of TMS coils and proposal of preventive measures

It is well-known that administering transcranial magnetic stimulation (TMS) stimuli with different current directions can yield different neurophysiological outcomes, such as a higher motor threshold and a longer latency after inducing anterior –posterior (AP)- as compared to PA-directed currents in the primary motor cortex (M1), probably due to distinct neuronal pathways being involved [1,2]. As a result, being correctly informed about the current direction of a TMS coil is crucial in TMS research, amongst others to ensure a correct cho ice, interpretation, and reporting of the experimental parameters [3].

Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - April 12, 2023 Category: Neurology Authors: Melina Hehl, Koen Cuypers Source Type: research