Modeling hemoglobin levels of patients chronically transfused with red blood cells

DISCUSSION: The endogenous Hb level is introduced in the HMB model which represents the patient's self-contribution to overall Hb levels via the autologous RBC lifecycle and was estimated to be 5.0 g/dL for patients with MDS or thalassemia. Transfusion therapy approaches and complementary therapeutics can target multiple, unique model inputs while monitoring net, overall impact on transfusion efficacy. Applying the HMB model to fit individual patient Hb fluctuations will be explored in the future.PMID:37005945 | DOI:10.1111/trf.17305
Source: Transfusion - Category: Hematology Authors: Source Type: research