Allele-specific chromatin looping promotes IRF5-dependent autoimmunity

Nature Reviews Rheumatology, Published online: 03 April 2023; doi:10.1038/s41584-023-00956-yA comprehensive analysis has identified chromatin looping as the mechanism that underlies the association of a pleiotropic genetic variant with several autoimmune diseases.

https://www.nature.com/articles/s41584-023-00956-y

Source: Nature Reviews Rheumatology - April 3, 2023 Category: Rheumatology Authors: Robert Phillips Source Type: research

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