A case of comma-shaped fibrillary glomerulonephritis

We present a case of a 77-year-old male with multiple co-morbidities who underwent a renal biopsy for progressive loss of renal function. Examination by electron microscopy revealed glomerular deposits within which were numerous randomly orientated 22 nanometre mean diameter curvilinear fibrils, consistent with a rare form of fibrillary glomerulonephritis. Review of the literature has revealed just one similar case. The investigative work up and histological findings are discussed along with the clinical implications of making a diagnosis of fibrillary glomerulonephritis.
Source: Diagnostic Histopathology - Category: Pathology Authors: Tags: Short case Source Type: research