Fibrosis in neovascular age-related macular degeneration: A review of definitions based on clinical imaging
Despite the success of antiangiogenic therapy in controlling exudation in neovascular age-related macular degeneration (nAMD), the involvement of the outer retina in fibrosis results in gradual vision loss over time. The development of drugs that prevent or ameliorate fibrosis in nAMD requires that it is accurately detected and quantified with reliable endpoints and identification of robust biomarkers. Achievement of such an aim is currently challenging due to the lack of a consensus definition of fibrosis in nAMD.
Source: Survey of Ophthalmology - Category: Opthalmology Authors: Isabel Bachmeier, Beatriz Garcia Armendariz, Siqing Yu, Ralf Josef J äger, Andreas Ebneter, Carl Glittenberg, Daniel Pauleikhoff, SriniVas R Sadda, Usha Chakravarthy, Sascha Fauser Source Type: research