Defining the roles of arrestin2 and arrestin3 in vasoconstrictor receptor desensitization in hypertension.

In conclusion, arrestin2 and 3 expression is elevated in resistance arteries during the emergence of the early hypertensive phenotype, which underlies an enhanced ability to desensitize vasoconstrictor signalling and vessel contraction. Such regulatory changes may act to compensate for increased vasoconstrictor-induced vessel contraction. PMID: 25972452 [PubMed - as supplied by publisher]

http://www.ncbi.nlm.nih.gov/pubmed/25972452?dopt=Abstract

Source: Am J Physiol Cell Ph... - May 13, 2015 Category: Cytology Authors: Willets JM, Nash CA, Rainbow RD, Nelson CP, Challiss RJ Tags: Am J Physiol Cell Physiol Source Type: research

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