PROTAC ’ing oncoproteins: targeted protein degradation for cancer therapy

Molecularly targeted cancer therapies substantially improve patient outcomes, although the durability of their effectiveness can be limited. Resistance to these therapies is often related to adaptive changes i...

Source: Molecular Cancer - March 30, 2023 Category: Cancer & Oncology Authors: Jeremy M. Kelm, Deepti S. Pandey, Evan Malin, Hussein Kansou, Sahil Arora, Raj Kumar and Navnath S. Gavande Tags: Review Source Type: research