APOBEC3-mediated mutagenesis in cancer: causes, clinical significance and therapeutic potential

Apolipoprotein B mRNA-editing enzyme, catalytic polypeptides (APOBECs) are cytosine deaminases involved in innate and adaptive immunity. However, some APOBEC family members can also deaminate host genomes to g...

Source: Journal of Hematology and Oncology - March 28, 2023 Category: Hematology Authors: Kelly Butler and A. Rouf Banday Tags: Review Source Type: research