Circulating and urinary tumour DNA in urothelial carcinoma — upper tract, lower tract and metastatic disease

Nature Reviews Urology, Published online: 28 March 2023; doi:10.1038/s41585-023-00725-2Non-invasive liquid biopsies such as plasma circulating tumour DNA (ctDNA) and urinary tumour DNA (utDNA) are promising tools for urothelial carcinoma diagnosis and management. In this Review, the authors provide an overview of the different liquid biopsy technologies available, and discuss the current state as well as future perspectives of ctDNA and utDNA application in urothelial carcinoma clinical care.

Source: Nature Reviews Urology - March 28, 2023 Category: Urology & Nephrology Authors: Kyle M. Rose Heather L. Huelster Joshua J. Meeks Bishoy M. Faltas Guru P. Sonpavde Seth P. Lerner Jeffrey S. Ross Philippe E. Spiess G. Daniel Grass Rohit K. Jain Ashish M. Kamat Aram Vosoughi Liang Wang Xuefeng Wang Roger Li Source Type: research