Epigenetic aging and PTSD outcomes in the immediate aftermath of trauma

CONCLUSIONS: Our findings shed new light on the relation between biological aging and trauma-related phenotypes, suggesting that GrimAge measured at the time of trauma predicts PTSD trajectories and is associated with relevant brain alterations. Furthering these findings has the potential to enhance early prevention and treatment of posttraumatic psychiatric sequelae.PMID:36951141 | DOI:10.1017/S0033291723000636

Source: Psychological Medicine - March 23, 2023 Category: Psychiatry Authors: Anthony S Zannas Sarah D Linnstaedt Xinming An Jennifer S Stevens Nathaniel G Harnett Alyssa R Roeckner Katelyn I Oliver David R Rubinow Elisabeth B Binder Karestan C Koenen Kerry J Ressler Samuel A McLean Source Type: research