Impaired circadian rhythm may disturb epithelialization in the wound healing of the skin in diabetic mice

Organisms have an internal circadian clock entrained by environmental cues. In mammals, the suprachiasmatic nucleus, located in the anterior part of the hypothalamus, sets the timing of the body ’s internal clock every morning by light signals from the retina [1]. Of note, the skin is governed by autonomous clock (as are other peripheral organs), as suggested by time-dependent variations of the skin barrier function [1,2].

Source: Journal of Dermatological Science - March 21, 2023 Category: Dermatology Authors: Junko Okano, Miwako Katagi, Takahiko Nakagawa, Hideto Kojima Source Type: research