Exosome-derived circCCAR1 promotes CD8  + T-cell dysfunction and anti-PD1 resistance in hepatocellular carcinoma

Circular RNAs (circRNAs) can be encapsulated into exosomes to participate in intercellular communication, affecting the malignant progression of a variety of tumors. Dysfunction of CD8  + T cells is the main fa...

Source: Molecular Cancer - March 18, 2023 Category: Cancer & Oncology Authors: Zongqiang Hu, Gang Chen, Yingpeng Zhao, Hongqiang Gao, Laibang Li, Yanfeng Yin, Jie Jiang, Li Wang, Yuanyi Mang, Yang Gao, Shengning Zhang, Jianghua Ran and Li Li Tags: Research Source Type: research