The era of cryptic exons: implications for ALS-FTD

TDP-43 is an RNA-binding protein with a crucial nuclear role in splicing, and mislocalises from the nucleus to the cytoplasm in a range of neurodegenerative disorders. TDP-43 proteinopathy spans a spectrum of ...

Source: Molecular Neurodegeneration - March 15, 2023 Category: Neurology Authors: Puja R. Mehta, Anna-Leigh Brown, Michael E. Ward and Pietro Fratta Tags: Review Source Type: research