Endovascular therapy might be a treatment option for mild stroke due to proximal occlusions but not M2 occlusions

We appreciate the letter from Zheng et al1 suggesting that the random effects model, not the fixed effects model, should be used to pool the results for our meta-analysis.2 In a sensitivity test, pooled results from the random effects model did not significantly show that endovascular therapy (EVT) compared with best medical management was associated with a higher rate of being disability free for patients with acute ischemic stroke (AIS) with National Institutes of Health Stroke Scale (NIHSS) scores of ≤5 due to proximal internal carotid artery (ICA) or middle cerebral artery M1 occlusions. However, the main point of this meta-analysis was to highlight the importance of knowledge about specific vessel occlusion sites in decision making for AIS with NIHSS scoresof ≤5 due to vessel occlusions in the anterior circulation, and the results obtained from the random effects model were consistent with the results obtained from the...
Source: Journal of NeuroInterventional Surgery - Category: Neurosurgery Authors: Tags: Letter Source Type: research