Breakthrough in tinnitus research could lead to testable model

A major breakthrough has been made that provides new insights into how tinnitus, and the often co-occurring hyperacusis, might develop and be sustained. Tinnitus is largely a mystery, a phantom sound heard in the absence of actual sound. Tinnitus patients "hear" ringing, buzzing or hissing in their ears much like an amputee might "feel" pain in a missing limb. It is a symptom, not a disease, and though exposure to loud noise may cause it, some cases have no apparent trigger.
Source: ScienceDaily Headlines - Category: Science Source Type: news

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To the Editor In a report on 21 US diplomatic staff who became unwell in Cuba, the authors rejected the possibility of a functional neurological disorder as the etiology. We disagree. The accompanying Editorial pointed out that functional neurological disorders are genuine and not malingering. Patients with functional disorders typically pass cognitive tests of effort, and there is no epidemiological evidence to suggest that they seek time away from the workplace. Functional disorders are typically persistent and commonly coexist with, or are triggered by, minor pathophysiological or psychophysiological processes. In many ...
Source: JAMA - Category: General Medicine Source Type: research
CONCLUSIONS: Although a number of studies aimed to evaluate whether or not one type of cerumenolytic is more effective than another, there is no high-quality evidence to allow a firm conclusion to be drawn and the answer remains uncertain.A single study suggests that applying ear drops for five days may result in a greater likelihood of complete wax clearance than no treatment at all. However, we cannot conclude whether one type of active treatment is more effective than another and there was no evidence of a difference in efficacy between oil-based and water-based active treatments.There is no evidence to show that using ...
Source: Cochrane Database of Systematic Reviews - Category: General Medicine Authors: Tags: Cochrane Database Syst Rev Source Type: research
ConclusionCameron ulcer is a rare cause of iron deficiency anemia from chronic blood loss. It is fatal but easily treatable ulcer at hiatal hernia. It very rare in pediatrics age particularly under five children and high index of suspicion is lifesaving.
Source: Journal of Pediatric Surgery Case Reports - Category: Surgery Source Type: research
Publication date: Available online 6 April 2018Source: Journal of Taibah University Medical SciencesAuthor(s): Sylves Patrick, Chan Hui-Tze, Wan Hitam Wan-Hazabbah, Embong Zunaina, Yaakub Azhany, Ahmad Tajudin Liza-SharminiAbstractManagement of inflammation after surgery for recalcitrant anterior uveitis is challenging. Herein, we report successful treatment using intracameral injection of recombinant tissue plasminogen activator (rtPA) in two patients with recalcitrant anterior uveitis, due to infective uveitis and Vogt–Koyanagi–Harada disease, respectively. A 40-year-old woman presented with bilateral redness...
Source: Journal of Taibah University Medical Sciences - Category: Universities & Medical Training Source Type: research
ConclusionBased on literature studied, there is no therapeutic response of tinnitus to transcranial direct current stimulation.ResumoIntroduçãoDevido à subjetividade do diagnóstico do zumbido e a suas diversas etiologias, o estabelecimento de um tratamento eficaz é complexo. Neste contexto surge a transcranial direct current stimulation, uma opção não invasiva, acessível para grande parte dos pacientes, e que tem apresentado bons resultados no tratamento de outros sintomas como dor crônica.ObjetivoAvaliar a resposta terapêutica do zumbido ao transcr...
Source: Brazilian Journal of Otorhinolaryngology - Category: ENT & OMF Source Type: research
Publication date: Available online 26 June 2018Source: Interdisciplinary NeurosurgeryAuthor(s): Natália R. Ferreira, Aleli T. Oliveira, Marcos F. DosSantos, Valéria Battistella, Paulo R.V. Bahia, Antônio C.P. Carvalho, André Antonio MonteiroAbstractFacial nerve schwannoma (FNS) is an uncommon benign tumor that arises from the Schwann cells of the facial nerve (FN). Although rare, this is the most frequent type of FN tumor, potentially affecting any segment of the nerve. Nevertheless, a higher incidence of intracranial lesions and a predilection for the geniculate ganglion has been reported. Heari...
Source: Interdisciplinary Neurosurgery - Category: Neurosurgery Source Type: research
ConclusionBased on literature studied, there is no therapeutic response of tinnitus to transcranial direct current stimulation.ResumoIntroduçãoDevido à subjetividade do diagnóstico do zumbido e a suas diversas etiologias, o estabelecimento de um tratamento eficaz é complexo. Neste contexto surge a transcranial direct current stimulation, uma opção não invasiva, acessível para grande parte dos pacientes, e que tem apresentado bons resultados no tratamento de outros sintomas como dor crônica.ObjetivoAvaliar a resposta terapêutica do zumbido ao transcr...
Source: Brazilian Journal of Otorhinolaryngology - Category: ENT & OMF Source Type: research
Publication date: Available online 6 April 2018Source: Journal of Taibah University Medical SciencesAuthor(s): Sylves Patrick, Chan Hui-Tze, Wan Hitam Wan-Hazabbah, Embong Zunaina, Yaakub Azhany, Ahmad Tajudin Liza-SharminiAbstractManagement of inflammation after surgery for recalcitrant anterior uveitis is challenging. Herein, we report successful treatment using intracameral injection of recombinant tissue plasminogen activator (rtPA) in two patients with recalcitrant anterior uveitis, due to infective uveitis and Vogt–Koyanagi–Harada disease, respectively. A 40-year-old woman presented with bilateral redness...
Source: Journal of Taibah University Medical Sciences - Category: Universities & Medical Training Source Type: research
Publication date: Available online 26 June 2018Source: Interdisciplinary NeurosurgeryAuthor(s): Natália R. Ferreira, Aleli T. Oliveira, Marcos F. DosSantos, Valéria Battistella, Paulo R.V. Bahia, Antônio C.P. Carvalho, André Antonio MonteiroAbstractFacial nerve schwannoma (FNS) is an uncommon benign tumor that arises from the Schwann cells of the facial nerve (FN). Although rare, this is the most frequent type of FN tumor, potentially affecting any segment of the nerve. Nevertheless, a higher incidence of intracranial lesions and a predilection for the geniculate ganglion has been reported. Heari...
Source: Interdisciplinary Neurosurgery - Category: Neurosurgery Source Type: research
With a global incidence estimated to be about 106 per 100,000 population, TBI is a leading cause of trauma-related disability 15. In the US more than 1.7 million injuries occur per year resulting in 250,000 hospitalizations and 52,000 deaths 9. The majority (75-80%) of all TBI cases are, however, mild and are accompanied by the rapid resolution of the immediate symptoms including disorientation, dizziness, tinnitus, nausea and balance problems 24. The incidence of TBI is higher overall in males than females, and is particularly common in the very young, adolescents and elderly 3.
Source: The Journal of Pain - Category: Materials Science Authors: Tags: Original Reports Source Type: research
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