Nasal Presentations of Rosai-Dorfman Disease: Clinical Manifestation and Treatment Outcomes

CONCLUSIONS: Diffuse lesions in nasal cavity and sinuses, and even widely affected nasal skull base, laryngopharynx, orbit, and cavernous sinus, should be considered the possibility of Rosai-Dorfman disease. Characteristic immunohistochemical staining is helpful for the diagnosis. Endoscopic surgical therapy remains the mainstream treatment for patients enduring an unbearable course. Oral corticosteroid administration serves as an adjuvant therapy for first-line treatments.PMID:36884341 | DOI:10.1177/01455613231162226

Source: Ear, Nose and Throat Journal - March 8, 2023 Category: ENT & OMF Authors: Haoyuan Xu Huankang Zhang Wanpeng Li Chen Zhang Huan Wang Dehui Wang Source Type: research