Craniofacial Fibrous Dysplasia: Clinical and Therapeutic Implications

This study aims to review diagnosis, potential complications, and clinical management in craniofacial fibrous dysplasia.Recent FindingsFibrous dysplasia (FD) is a rare mosaic disorder in which normal bone and marrow are replaced with expansile fibro-osseous lesions. Disease presents along a broad spectrum and may be associated with extraskeletal features as part of McCune-Albright syndrome (MAS). The craniofacial skeleton is one of the most commonly impacted areas in FD, and its functional and anatomical complexities create unique challenges for diagnosis and management.SummaryThis review summarizes current approaches to diagnosis and management in FD/MAS, with emphasis on the clinical and therapeutic implications for the craniofacial skeleton.
Source: Current Osteoporosis Reports - Category: Orthopaedics Source Type: research