Extracellular protein homeostasis in neurodegenerative diseases

Nature Reviews Neurology, Published online: 24 February 2023; doi:10.1038/s41582-023-00786-2Wilson et al. review our current knowledge of the extracellular proteostasis system that protects the brain from the pathological consequences of extracellular protein aggregation. They discuss growing evidence that impairment of this system contributes to neuronal death in neurodegenerative diseases.

Source: Nature Reviews Neurology - February 24, 2023 Category: Neurology Authors: Mark R. Wilson Sandeep Satapathy Michele Vendruscolo Source Type: research