An amended in vitro-in vivo extrapolation model that accounts for first pass clearance effects on chemical bioaccumulation in fish

Environ. Sci.: Processes Impacts, 2023, Accepted Manuscript DOI: 10.1039/D2EM00522K, PaperLeslie J Saunders, John Nichols, Jon Arnot, James M Armitage, Frank Wania Measured rates of in vitro intrinsic clearance for fish may be extrapolated to the whole animal as a means of estimating a whole-body biotransformation rate constant (kB; d-1). This estimate... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - J. Environ. Monit. latest articles - Category: Environmental Health Authors: Source Type: research