Molecules, Vol. 28, Pages 2019: Molecular Docking and In Vitro Studies of Ochratoxin A (OTA) Biodetoxification Testing Three Endopeptidases

This study is the first attempt to demonstrate that: (i) bromelain and trypsin can hydrolyse OTA in acidic pH conditions with low efficiency and (ii) the metalloendopeptidase was an effective OTA bio-detoxifier. This study confirmed α-ochratoxin as a final product of the enzymatic reactions in real-time practical information on OTA degradation rate, since in vitro experiments simulated the time that food spends in poultry intestines, as well as their natural pH and temperature conditions.

Source: Molecules - February 21, 2023 Category: Chemistry Authors: Pablo C ésar Orozco-Cortés Cesar Mateo Flores-Ort íz Luis Barbo Hern ández-Portilla Josefina V ázquez Medrano Olga Nelly Rodr íguez-Peña Tags: Article Source Type: research