Transcriptome-wide assessment of N6-methyladenosine modification identifies different gene expression and infection-associated pathways in Treponema pallidum-infected macrophage

Treponema pallidum (Tp) is a widespread and destructive pathogen that leads to syphilis. As the acknowledged executor of host immunity, macrophage plays vital roles in combating the invasion and migration of Tp. However, the mechanisms of these processes are largely unknown, especially the critical driver genes and associated modifications.

Source: Journal of Dermatological Science - February 18, 2023 Category: Dermatology Authors: Zhijia Li, Litian Zhang, Yinbo Jiang, Xiaoxin Lin, Yuhui Liao, Bin Yang, Muzhou Teng Source Type: research