A case of sclerosing odontogenic carcinoma: a rare entity

Sclerosing odontogenic carcinoma (SOC) is a very rare entity, first recognized in the WHO 4th edition (2017). It is a highly infiltrative intraosseous jaw tumour with small nests, strands and cords of cells showing only mild cytological atypia, surrounded by a dense fibrocollagenous stroma. The lesion frequently infiltrates adjacent tissues and bony structures and demonstrates perineural and intraneural invasion. The malignant islands of cells may be compressed by the stroma, making them difficult to identify.
Source: Diagnostic Histopathology - Category: Pathology Authors: Tags: Short case Source Type: research