Origins and immunopathogenesis of autoimmune central nervous system disorders

This article reviews key pathogenic mechanisms underlying the development of CNS autoimmunity, focusing on the role of autoantibodies that target neuronal and/or glial cell-surface antigens. The authors consider novel therapeutic approaches based on knowledge of the immunopathogenesis of autoimmune CNS disorders.

Source: Nature Reviews Neurology - February 14, 2023 Category: Neurology Authors: Sudarshini Ramanathan Fabienne Brilot Sarosh R. Irani Russell C. Dale Source Type: research