Evaluation of the effectiveness of maternal immunization against pertussis in Alberta using agent-based modeling: A Canadian immunization research network study
CONCLUSIONS: Our model predicts significant reduction in future pertussis cases in infants due to maternal vaccination, with immunological blunting slightly moderating its effectiveness. The model is most sensitive to maternal vaccination coverage. The interruption of exposure pathways plays a role in the reduction of pertussis burden in infants due to maternal immunization. The effect of maternal immunization on population other than infants remains to be elucidated.PMID:36775775 | DOI:10.1016/j.vaccine.2022.12.071
Source: Vaccine - Category: Allergy & Immunology Authors: Karsten Hempel Wade McDonald Nathaniel D Osgood David Fisman Scott A Halperin Natasha Crowcroft Nicola P Klein Pejman Rohani Alexander Doroshenko Source Type: research
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