Association of infant Rib and Alp1 surface protein N-terminal domain immunoglobulin G and invasive Group B Streptococcal disease in young infants

DISCUSSION: Lower serum RibN and Alp1N IgG GMC were evident in infants with invasive GBS disease compared with controls born to women colonized with GBS expressing the homotypic protein. These data support the evaluation of Alp family proteins as potential vaccine candidates against invasive GBS disease.PMID:36754766 | DOI:10.1016/j.vaccine.2023.01.071

Source: Vaccine - February 8, 2023 Category: Allergy & Immunology Authors: Ziyaad Dangor Gaurav Kwatra Andrzej Pawlowski Per B Fisher Alane Izu Sanjay G Lala Bengt Johansson-Lindbom Shabir A Madhi Source Type: research