Associations with non-persistence with intra-vitreal therapy for neovascular age-related macular degeneration at 24 months

Conclusions: Non-persistence with treatment was common, especially in the first year of treatment, and was often associated with a decrease in visual acuity. Treatment site, baseline visual acuity and age were the strongest predictors of treatment non-persistence before day 720. U nderstanding and addressing reasons for non-persistence are important to ensure that effective but expensive treatments are used cost-effectively and to maintain acuity. Variation in non-persistence between sites, even after adjustment for other variables, suggests that local factors in treatment pr ovision may be particularly important.
Source: Ophthalmologica - Category: Opthalmology Source Type: research