Cashew and Shrimp Oral Immunotherapy-Induced Changes in Allergen-Reactive CD4+ T Cells

In this study, the participants were treated with increasing dose of cognate allergen for 52 weeks followed by 6 weeks of avoidance. Participants successfully desensitized post-OIT were classified into two groups, namely SU4043 (n=23) and SU2043 (n=5) based on the cumulative tolerated allergen protein dose of 4043 mg and 2043 mg respectively during the post-avoidance (i.e., week 58) oral food challenge.

Source: Journal of Allergy and Clinical Immunology - February 1, 2023 Category: Allergy & Immunology Authors: Andrea Fernandes, Sheena Gupta, Shu Cao, Ella Parsons, Sofia Maysel-Auslender, Diane Dunham, Shu-Chen Lyu, Jessica Rogers, Kristine Martinez, Sayantani Sindher, Monali Manohar, Holden Maecker, Kari Nadeau Source Type: research