Comparing models of information transfer in the structural brain network and their relationship to functional connectivity: diffusion versus shortest path routing

We examined the extent to which each of these models can account for the structure –function relationship of interest using graph theory measures that are exclusively based on each model. This analysis was performed on multiple parcellations of the Human Connectome Project using multiple approaches, which all converged on the same finding. We found that the diffusion model accou nts for much more variance in functional connectivity than the shortest path routing model, suggesting that the diffusion model is better suited to describing the structure–function relationship in the human brain at the macroscale.

Source: Anatomy and Embryology - February 1, 2023 Category: Anatomy Source Type: research