Postural misperception: a biomarker for persistent postural perceptual dizziness

Introduction Persistent postural perceptual dizziness (PPPD) describes a persistent sensation of dizziness and/or unsteadiness (without vertigo) aggravated by upright posture that generates increased postural sway.1 Here, we introduce a novel measure of perceived instability to investigate the relationship between observed sway and perceived instability in patients with PPPD compared with patients with persistent ‘objective’ instability due to bilateral vestibulopathy (BV). MethodsParticipants Overall, 19 individuals with PPPD, according to the diagnostic criteria of the International Classification of Vestibular Diseases and 10 disease controls with BV (confirmed with objective vestibular function testing), were included following informed consent. PPPD patients were randomly allocated to an ‘intervention’ (n=7) and ‘no intervention’ group (n=12). Ten healthy controls were also recruited to validate the novel measure of perceived instability. Measurement of observed sway All participants performed three identical 20 s trials of quiet standing on a firm surface...
Source: Journal of Neurology, Neurosurgery and Psychiatry - Category: Neurosurgery Authors: Tags: PostScript Source Type: research