Gasdermins and pyroptosis in the kidney

Nature Reviews Nephrology, Published online: 03 January 2023; doi:10.1038/s41581-022-00662-0Pyroptosis is a form of regulated cell death that is mediated by the membrane-targeting, pore-forming gasdermin family of proteins. Here, the authors provide an overview of the basic biology of gasdermins and pyroptosis with a focus on the mechanisms by which these proteins may contribute to kidney disease.
Source: Nature Reviews Nephrology - Category: Urology & Nephrology Authors: Source Type: research