A preliminary study of hydrocodone and hydromorphone to oxycodone ratios for distinguishing impurities from independent opioid use

CONCLUSIONS: Hydrocodone and/or hydromorphone are detectable in patients taking only oxycodone and can likely be identified as an impurity if their calculated ratio to oxycodone is <1 %. Further validation of the ratios in a larger sample size is recommended.PMID:36535386 | DOI:10.1016/j.clinbiochem.2022.12.009

Source: Clinical Biochemistry - December 19, 2022 Category: Biochemistry Authors: Ibrahim Choucair Cristina Figueroa Villalba Michael A Vera Gina Cassella-Mclane Thomas J S Durant Joe M El-Khoury Source Type: research