Genome- and transcriptome-wide association studies of 386,000 Asian and European-ancestry women provide new insights into breast cancer genetics
Using data from 386,000 Asian- and European-ancestry women, we conducted extensive genome- and transcriptome-wide association studies that identified 222 risk loci and 137 genes in association with breast cancer risk. These studies, along with pathway analyses, provide a comprehensive understanding of and new biological insights into the genetics of breast cancer.
Source: The American Journal of Human Genetics - Category: Genetics & Stem Cells Authors: Guochong Jia, Jie Ping, Xiang Shu, Yaohua Yang, Qiuyin Cai, Sun-Seog Kweon, Ji-Yeob Choi, Michiaki Kubo, Sue K. Park, Manjeet K. Bolla, Joe Dennis, Qin Wang, Xingyi Guo, Bingshan Li, Ran Tao, Kristan J. Aronson, Tsun L. Chan, Yu-Tang Gao, Mikael Hartman, Tags: Article Source Type: research