Hepatic fat as a novel marker for high-risk coronary atherosclerotic plaque features in familial hypercholesterolaemia

Hepatic steatosis has been associated with increased risk of coronary artery disease. Individuals with familial hypercholesterolaemia have accelerated but variable progression of coronary artery disease. We investigated whether hepatic steatosis is associated with novel coronary atherosclerosis biomarkers in adults with heterozygous familial hypercholesterolaemia, using comprehensive coronary computed tomographic angiography.

Source: Metabolism - Clinical and Experimental - November 30, 2022 Category: Biomedical Science Authors: Gavin Huangfu, Biyanka Jaltotage, Jing Pang, Nick S.R. Lan, Arun Abraham, Jacobus Otto, Abdul R. Ihdayhid, Jamie M. Rankin, Benjamin J.W. Chow, Gerald F. Watts, Oyekoya T. Ayonrinde, Girish Dwivedi Source Type: research