Adipocytokine plasma concentrations reflect influence of inflammation but not body mass index (BMI) on clinical outcomes of COVID ‐19 patients: A prospective observational study from the Netherlands
In conclusion, leptin and adiponectin are associated with BMI, but not with clinical outcomes and inflammation in COVID-19 patients. In contrast, resistin is not associated with BMI, but high concentrations are associat ed with worse clinical outcomes and more pronounced inflammation. Therefore, it is unlikely that BMI-related adipocytokines or differences in the inflammatory response underlie obesity as a risk factor for severe COVID-19.
Source: Clinical Obesity - Category: Eating Disorders & Weight Management Authors: Aline H. Nooijer,
Emma J. Kooistra,
Inge Grondman,
Nico A. F. Janssen,
Leo A. B. Joosten,
Frank L. Veerdonk,
Matthijs Kox,
Peter Pickkers,
Mihai G. Netea, on behalf of the RCI ‐COVID‐19 study group Tags: ORIGINAL RESEARCH Source Type: research