Persistent diabetic macular edema: Definition, incidence, biomarkers and treatment methods

Intravitreal anti-vascular endothelial growth factor (anti-VEGF) treatment has drastically improved the visual and anatomical outcomes in patients with diabetic macular edema (DME); however, success is not always guaranteed, and a proportion of these eyes demonstrate persistent DME (pDME) despite intensive treatment. While standardized criteria to define these treatment-resistant eyes have not yet been established, many studies refer to eyes with no clinical response or an unsatisfactory partial response as having pDME.
Source: Survey of Ophthalmology - Category: Opthalmology Authors: Tags: Review article Source Type: research