Flavonoid glycosides and ellagic acid cognates from defatted African mango ( < em > Irvingia gabonensis < /em > ) seed kernel

Nat Prod Res. 2022 Nov 1:1-10. doi: 10.1080/14786419.2022.2140151. Online ahead of print.ABSTRACTSeventeen compounds of diverse classes including four flavonoid glycosides, five ellagic acid derivatives, and eight other metabolites were isolated from the methanolic extract of the defatted seed kernel of Irvingia gabonensis. Among the isolates, quercetin 3-O-methyl-4'-[α-L-rhamnopyranosyl-(1→3)]-O-α-L-rhamnopyranoside (1) and 3,3'-di-O-methyl-4'-O-α-L-rhamnopyranosylellagic acid 4-sulfate ester (5) were found to be previously undescribed. Structure elucidation was mainly achieved by the interpretation of 1D and 2D NMR and HRESIMS spectral data. Though compound 6 was previously reported, its 13C NMR data is being reported herein for the first time. To the best of our literature search knowledge, this is the first phytochemical report on I. gabonensis seed kernels.PMID:36318869 | DOI:10.1080/14786419.2022.2140151

Source: Natural Product Research - November 1, 2022 Category: Biochemistry Authors: Fazila Zulfiqar Zulfiqar Ali Alvaro M Viljoen Amar G Chittiboyina Ikhlas A Khan Source Type: research