New-onset Obesity After Lung Transplantation: Incidence, Risk Factors, and Clinical Outcomes

Background. Lung transplant (LTx) recipients who gain weight after transplantation may experience an upward shift in body mass index (BMI) that places them in the obese category. The incidence, risk factors, and impact on metabolic health and mortality of new-onset obesity have not been documented in the LTx setting. Methods. This single-center retrospective study included 564 LTx recipients. Individuals were stratified according to their BMI trajectories from pretransplant evaluation up to 10 y posttransplant. New-onset obesity was defined as a pretransplant BMI 30 kg/m2. The incidence, risk factors, and posttransplant diabetes mellitus, metabolic syndrome, and mortality of recipients with new-onset obesity were compared with those of nonobese (BMI 30 kg/m2, pre/post-LTx), and obese recipients with weight loss (BMI>30 kg/m2 pre-LTx, BMI
Source: Transplantation - Category: Transplant Surgery Tags: Original Clinical Science—General Source Type: research