The synthetic lethality of targeting cell cycle checkpoints and PARPs in cancer treatment
Continuous cell division is a hallmark of cancer, and the underlying mechanism is tumor genomics instability. Cell cycle checkpoints are critical for enabling an orderly cell cycle and maintaining genome stabi...
Source: Journal of Hematology and Oncology - Category: Hematology Authors: Shuangying Li, Liangliang Wang, Yuanyuan Wang, Changyi Zhang, Zhenya Hong and Zhiqiang Han Tags: Review Source Type: research