A multipurpose panel of microhaplotypes for casework

Microhaplotypes (MHs) are SNP-based multiallelic loci that have several advantages over individual SNPs and short tandem repeats (STRs). For several years we have been searching for better MHs based on the effective number of alleles at a locus (Ae) and the locus informativeness for population relationships (In) with thoughts of incorporating MHs into casework. We genotyped a multiplex of our best 90 MHs on 79 populations. We have ranked the 90 by Ae and analyzed the top 24 to evaluate their potential value in forensic casework.
Source: Forensic Science International: Genetics Supplement Series - Category: Forensic Medicine Authors: Source Type: research