When single-inhaler triple therapy is a preferred option in asthma management ?

Mohamed S Al-Moamary, Riyad Al-Lehebi, Majdy M Idrees, Mohammed O ZeitouniAnnals of Thoracic Medicine 2022 17(4):185-188 Asthma control is the main goal of management. Unfortunately, most asthma patients with moderate–severe asthma remain uncontrolled despite receiving standard treatment of inhaled corticosteroids (ICS) with long-acting β2 agonists (LABA). The addition of long-acting antimuscarinic agents (LAMA) has been shown to improve different aspects of asthma control, including symptoms, lung functions, and probably exacerbations. Such an option could be considered for low-T2 asthma phenotype. Umeclidinium and glycopyrronium bromide are other LAMA agents that have been recently made available in combination with ICS and LABA in single-inhaler triple therapy (SITT) devices. Here, we discuss the position of SITT as a new novel therapeutic option in asthma management and its clinical benefits, potential cost saving, and improved compliance.
Source: Annals of Thoracic Medicine - Category: Respiratory Medicine Authors: Source Type: research