Maternal pre ‐pregnancy body mass index and offspring with overweight/obesity at preschool age: The possible role of epigenome‐wide DNA methylation changes in cord blood

ConclusionsDNA methylation inFOXN3 andAHRR is associated with overweight/obesity in preschool-aged children, and the methylation inFOXN3 andZNF264 might be associated with children's BMI-z score.FOXN3 methylation may be associated with maternal pre-pregnancy BMI, suggesting its potential role in the children's BMI-z score or overweight/obesity. Our results provide novel insights into the mechanisms of children's obesity.

Source: Pediatric Obesity - September 14, 2022 Category: Eating Disorders & Weight Management Authors: Ruixia Chang, Yuanyuan Zhang, Jiahong Sun, Ke Xu, Chunan Li, Jingli Zhang, Wenhua Mei, Hongzhong Zhang, Jianduan Zhang Tags: ORIGINAL RESEARCH Source Type: research