Individualizing treatment of type 2 diabetes by targeting postprandial or fasting hyperglycaemia: Response to a basal vs a premixed insulin regimen by HbA1c quartiles and ethnicity.

CONCLUSION: At baseline, the contribution of FHG to overall hyperglycaemia predominated at all HbA1c quartiles, whereas PHG was more clinically relevant at lower HbA1c levels and with a greater response to insulin lispro mix 25. Asians had a greater proportion of PHG and a lesser response to either insulins compared with Caucasians. Thus, responses to diabetes drugs by baseline HbA1c and ethnicity are worth investigating to better target and individualize treatment. PMID: 25881510 [PubMed - as supplied by publisher]

http://www.ncbi.nlm.nih.gov/pubmed/25881510?dopt=Abstract

Source: Diabetes and Metabolism - April 13, 2015 Category: Endocrinology Authors: Scheen AJ, Schmitt H, Jiang HH, Ivanyi T Tags: Diabetes Metab Source Type: research