Genetics of ANCA-associated vasculitis: role in pathogenesis, classification and management

Nature Reviews Rheumatology, Published online: 15 September 2022; doi:10.1038/s41584-022-00819-yIn this Review, the authors summarize the genetic factors associated with anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV). They describe the findings from genetic association studies, their pathogenic significance and their implications for the classification, management and prognosis of AAV.

Source: Nature Reviews Rheumatology - September 15, 2022 Category: Rheumatology Authors: Giorgio Trivioli Ana Marquez Davide Martorana Michelangelo Tesi Andreas Kronbichler Paul A. Lyons Augusto Vaglio Source Type: research