Immunoglobulin A (De Novo) Vasculitis After mRNA Moderna COVID-19 Vaccination: A Case Report

Concurrent with the administration of vaccines for the novel coronavirus (COVID-19), there have been many reported adverse effects, and many of them anticipated as with any vaccine administration. This case report, however, focuses on a patient who, shortly after receiving the first dose of the Moderna COVID-19 vaccine, developed a pruritic maculopapular rash with typical distribution and clinical characteristics, along with high levels of immunoglobulin A (IgA), consistent with IgA vasculitis, formerly known as Henoch-Schonlein purpura. Although there are reported cases of IgA vasculitis after different vaccine administrations, to our knowledge, there are no reports of development of this condition after COVID-19 vaccination. The patient did not have any other triggering events or factors that could be attributed to the development of this pathology. This case describes the development of IgA vasculitis after the COVID-19 vaccination.
Source: Infectious Diseases in Clinical Practice - Category: Infectious Diseases Tags: Case Report Source Type: research