Deciphering the Pharmacological Mechanisms of Qidan Dihuang Decoction in Ameliorating Renal Fibrosis in Diabetic Nephropathy through Experimental Validation < em > In Vitro < /em > and < em > In Vivo < /em >

CONCLUSIONS: Taken together, our results suggest that QDD effectively alleviates diabetic renal injuries and fibrosis by inhibiting the PERK-eIF2α-ATF4 pathway and promoting autophagy in diabetic nephropathy.PMID:36091599 | PMC:PMC9463013 | DOI:10.1155/2022/4137578

Source: Evidence-based Complementary and Alternative Medicine - September 12, 2022 Category: Complementary Medicine Authors: Qiuer Liang Zhenyu Bai Ting Xie Hanqi Lu Lei Xiang Ke Ma Tianhao Liu Tingting Guo Liguo Chen Xiaoshan Zhao Ya Xiao Source Type: research