Involvement of AGE and Its Receptors in the Pathogenesis of Hypertension in Elderly People and Its Treatment

In conclusion, the AGE–RAGE axis could be involved in hypertension in elderly people. Treatment for hypertension in elderly people should be targeted at reduction of AGE levels in the body, prevention of AGE formation, degradation of AGE in vivo, downregulation of RAGE expression, blockade of AGE–RAGE interaction, upregulation of sRAGE expression, and use of antioxidants. [...] Thieme Medical Publishers, Inc. 333 Seventh Avenue, 18th Floor, New York, NY 10001, USAArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text
Source: International Journal of Angiology - Category: Cardiology Authors: Tags: Review Article Source Type: research