Serum Interleukin-6 and Weight loss in Antiretroviral-na ïve and Antiretroviral-treated Patients with HIV/AIDS: Relationships and Predictors

CONCLUSION: HIV infection is associated with elevation of serum interleukin-6, which likely contributes to weight and facial fat loss among the treatment-naïve participants; while HAART is associated with suppressed IL-6 levels, thereby ameliorating weight and facial fat loss. Inverse relationship exists between serum IL-6 and CD4+ count; serum IL-6 could differentiate between mild- to moderate and severe immunosuppressive states.PMID:36056868 | DOI:10.2174/1570162X20666220901085926

Source: Current HIV Research - September 3, 2022 Category: Infectious Diseases Authors: Tewogbade Adeoye Adedeji Nife Olamide Adedeji Abiodun Kofoworola Ajeigbe Olufemi Samuel Smith Olusola Akanni Jeje Michael Bimbo Fawale Abiodun Olabamiji Ajose Simeon Adelani Adebisi Adeyinka Abdulrasak Akande Bashiru Adekunle Okesina Source Type: research