Transcriptional comparison of Testicular Adrenal Rest Tumors with fetal and adult tissues

CONCLUSION: Our data suggest that TART is induced -most likely via activation of a cAMP/PKA dependent receptor- from a progenitor cell into a unique mature adrenal-like cell type, sometimes exhibiting both adrenal and testicular features.PMID:36047744 | DOI:10.1530/EJE-22-0143

Source: European Journal of Endocrinology - September 1, 2022 Category: Endocrinology Authors: Mariska A M Schr öder Fred C G J Sweep Antonius E van Herwaarden Rod T Mitchell Jitske Eliveld Ans M M van Pelt Alan E Rowan Darren Korbie Nike M M L Stikkelbroeck Hedi L Claahsen-van der Grinten Paul N Span Source Type: research